Twelve novel loci containing nearly 25 genes potentially associated with Parkinson’s disease have been identified in the largest, most genetically diverse study of the disease to date.Read More
Preclinical testing provides support for a novel method of recording large-scale neuronal activity, raising prospects for better understanding of behavioral changes in neurological disorders.
Preclinical and clinical studies are exploring whether pharmacologically augmenting hydrogen sulfide synthesis to inhibit thyroid hormone production may safely improve glioblastoma outcomes.
A study using systems biology and multi-omics suggests that sex-specific differences in immune responses, cellular metabolism and microglial immunometabolism play a key role in sex-related variability in pathogenesis and disease progression.
Cleveland Clinic is launching the Quantum Innovation Catalyzer Program, a chance for start-up companies in healthcare technology and life sciences to gain experience with quantum computing and apply it to their research and development work under expert guidance.
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A researcher explains the rationale for and goals of her investigations of blood-based biomarkers for Alzheimer’s disease specifically in women.
An early-career Cleveland Clinic researcher has devised a multipronged strategy that integrates advanced computational and experimental approaches to dementia research. The work has attracted $16 million in external grant funding in 2023 alone.
Researchers found that rodents use multiple strategies even in advanced stages of learning. They’re now working to apply these insights to neurological diseases in humans.
A team of scientists from Cleveland Clinic’s Lerner Research Institute, Johns Hopkins University School of Medicine and Johns Hopkins Drug Discovery has synthesized and tested a new class of gut-restricted oral therapies that shows promise in treating inflammatory bowel disease.
A Cleveland Clinic-led research team has identified a key protein-modifying mechanism that the Zika virus and other mosquito-transmitted flaviviruses use to hijack infected host cells and promote their own replication. The discovery raises the prospect of new therapeutics for flaviviruses, a category of viruses for which few drug treatments or vaccines currently exist.
A leading brain tumor researcher explains how the transfer of mitochondria from astrocytes may fuel glioblastoma growth.